Monday, October 17, 2011

On Pradaxa (dabigatran)

Dabigatran (Pradaxa) is an direct thrombin inhibitors oral anticoagulant. It is an alternative to warfarin. It has huge advantage  as  it does not require frequent blood tests for  INR monitoring.

Being an ICU physician it important to know that there is no specific antidote to reverse the anticoagulant effect of dabigatran in the event of a major bleeding event, unlike warfarin. Treatment is supportive.